By car Autostrada del Sole A1 Florence to Rome: If you are coming from the North, exit at Valdichiana - follow signs for Perugia. If you are coming from the South, exit at Orte, following signs to Perugia.

Autostrada Adriatica A14: If you are coming from the North, exit at Rimini (continue to Città di Castello) - Fano (continue to Gubbio). If you are coming from the South, exit at Ancona Nord (continue to Gubbio) - Pescara (continue to Terni via Aquila - Rieti) - Civitanova Marche (continue to Foligno - Perugia). Superstrada E45 Cesena - Orte crosses the whole of Umbria from top to bottom.